Showing posts with label Articles. Show all posts
Showing posts with label Articles. Show all posts

Thursday, 29 September 2016

Tricho Plus




Tricho Plus may be available in the countries listed below.


In some countries, this medicine may only be approved for veterinary use.

Ingredient matches for Tricho Plus



Ronidazole

Ronidazole is reported as an ingredient of Tricho Plus in the following countries:


  • Netherlands

International Drug Name Search

Alphosyl




In the US, Alphosyl is a member of the drug class miscellaneous topical agents and is used to treat Dermatitis, Psoriasis and Seborrheic Dermatitis.

Ingredient matches for Alphosyl



Allantoin

Allantoin is reported as an ingredient of Alphosyl in the following countries:


  • Ireland

International Drug Name Search

Wednesday, 28 September 2016

Uvédose




Uvédose may be available in the countries listed below.


Ingredient matches for Uvédose



Colecalciferol

Colecalciferol is reported as an ingredient of Uvédose in the following countries:


  • France

  • Luxembourg

International Drug Name Search

Avant




Avant may be available in the countries listed below.


Ingredient matches for Avant



Haloperidol

Haloperidol is reported as an ingredient of Avant in the following countries:


  • Malta

  • Taiwan

International Drug Name Search

Tiadenol




Scheme

Rec.INN

ATC (Anatomical Therapeutic Chemical Classification)

C10AX03

CAS registry number (Chemical Abstracts Service)

0006964-20-1

Chemical Formula

C14-H30-O2-S2

Molecular Weight

294

Therapeutic Category

Antilipemic agent

Chemical Name

Ethanol, 2,2'-[1,10-decanediylbis(thio)]bis-

Foreign Names

  • Tiadenolum (Latin)
  • Tiadenol (German)
  • Tiadénol (French)
  • Tiadenol (Spanish)

Generic Names

  • Tiadénol (OS: DCF)
  • Tiadenolo (OS: DCIT)
  • LL 1558 (IS)

Brand Name

  • Fonlipol
    SERP, Monaco

International Drug Name Search

Glossary

DCFDénomination Commune Française
DCITDenominazione Comune Italiana
ISInofficial Synonym
OSOfficial Synonym
Rec.INNRecommended International Nonproprietary Name (World Health Organization)

Click for further information on drug naming conventions and International Nonproprietary Names.

butorphanol Injection


bue-TOR-fa-nol


Commonly used brand name(s)

In the U.S.


  • Stadol

Available Dosage Forms:


  • Solution

Therapeutic Class: Analgesic


Pharmacologic Class: Opioid Agonist/Antagonist


Chemical Class: Opioid


Uses For butorphanol


Butorphanol injection is used to relieve pain. It may also be given before a surgery, when giving birth, or with general anesthesia before an operation.


Butorphanol injection belongs to the group of medicines called narcotic analgesics (pain medicines). It acts on the central nervous system (CNS) to relieve pain.


When butorphanol injection is used for a long time, it may become habit-forming, causing mental or physical dependence. However, people who have continuing pain should not let the fear of dependence keep them from using narcotics to relieve their pain. Mental dependence (addiction) is not likely to occur when narcotics are used for this purpose. Physical dependence may lead to withdrawal side effects if treatment is stopped suddenly. However, severe withdrawal side effects can usually be prevented by gradually reducing the dose over a period of time before treatment is stopped completely.


butorphanol is available only with your doctor's prescription.


Before Using butorphanol


In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For butorphanol, the following should be considered:


Allergies


Tell your doctor if you have ever had any unusual or allergic reaction to butorphanol or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.


Pediatric


Appropriate studies have not been performed on the relationship of age to the effects of butorphanol injection in the pediatric population. Safety and efficacy have not been established.


Geriatric


Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of butorphanol injection in the elderly. However, elderly patients may be more sensitive to the effects of butorphanol than younger adults, and are more likely to have age-related kidney problems, which may require caution and an adjustment in the dose for patients receiving butorphanol injection.


Pregnancy








Pregnancy CategoryExplanation
All TrimestersCAnimal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.

Breast Feeding


Studies in women suggest that this medication poses minimal risk to the infant when used during breastfeeding.


Interactions with Medicines


Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are receiving butorphanol, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.


Using butorphanol with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.


  • Alfentanil

  • Alphaprodine

  • Codeine

  • Dihydrocodeine

  • Fentanyl

  • Fospropofol

  • Hydrocodone

  • Hydromorphone

  • Levorphanol

  • Meperidine

  • Methadone

  • Morphine

  • Morphine Sulfate Liposome

  • Oxycodone

  • Oxymorphone

  • Propoxyphene

  • Sufentanil

  • Tapentadol

Interactions with Food/Tobacco/Alcohol


Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.


Other Medical Problems


The presence of other medical problems may affect the use of butorphanol. Make sure you tell your doctor if you have any other medical problems, especially:


  • Alcohol abuse, or history of or

  • Breathing problems (e.g., chronic obstructive pulmonary disease [COPD], cor pulmonale, hypoxia) or

  • CNS diseases or

  • Drug dependence, especially narcotic abuse or dependence, history of—Use with caution. May increase risk for more serious side effects.

  • Brain tumor or

  • Head injuries or

  • Increased pressure in the head—Some of the side effects of butorphanol injection can cause serious problems in people who have these medical problems.

  • Heart attack or

  • Heart or blood vessel problems or

  • Hypertension (high blood pressure)—Use with caution. May make these conditions worse.

  • Kidney disease or

  • Liver disease—Use with caution. The effects may be increased because of slower removal of the medicine from the body.

Proper Use of butorphanol


A nurse or other trained health professional will give you butorphanol. butorphanol is given as a shot into a muscle or through a needle placed in one of your veins.


Precautions While Using butorphanol


It is very important that your doctor check your progress while you are using butorphanol. This will allow your doctor to see if the medicine is working properly and to decide if you should continue to use it.


butorphanol will add to the effects of alcohol and other CNS depressants (medicines that can make you drowsy or less alert). Some examples of CNS depressants are antihistamines or medicine for allergies or colds; sedatives, tranquilizers, or sleeping medicine; other prescription pain medicine or narcotics; medicine for seizures or barbiturates; muscle relaxants; or anesthetics, including some dental anesthetics. Check with your doctor before taking any of the other medicines listed above while you are using butorphanol.


butorphanol may make you dizzy, drowsy, confused, or disoriented. Make sure you know how you react to butorphanol before you drive, use machines, or do anything else that could be dangerous if you are dizzy or not alert.


Using narcotics for a long time can cause severe constipation. To prevent this, your doctor may direct you to take laxatives, drink a lot of fluids, or increase the amount of fiber in your diet. Be sure to follow the directions carefully, because continuing constipation can lead to more serious problems.


Your doctor may want you to gradually reduce the amount you are using before stopping it completely. This may help prevent worsening of your condition and reduce the possibility of withdrawal symptoms, such as abdominal or stomach cramps, anxiety, fever, nausea, runny nose, sweating, tremors, or trouble with sleeping.


Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.


butorphanol Side Effects


Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.


Check with your doctor or nurse immediately if any of the following side effects occur:


Less common
  • Cough producing mucus

  • difficulty breathing

  • shortness of breath

  • tightness in chest

  • wheezing

Rare
  • Blurred vision

  • chest pain

  • confusion

  • dizziness, faintness, or lightheadedness when getting up from a lying or sitting position suddenly

  • fast, pounding, or irregular heartbeat or pulse

  • nervousness

  • pounding in the ears

  • slow or fast heartbeat

Incidence not known
  • Bluish lips or skin

  • false beliefs that cannot be changed by facts

  • not breathing

  • seizures

Get emergency help immediately if any of the following symptoms of overdose occur:


Symptoms of overdose
  • Change in consciousness

  • extremely shallow or slow breathing

  • irregular heartbeats

  • loss of consciousness

  • shortness of breath

  • swelling in hands and feet

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:


More common
  • Dizziness

  • nausea

  • sleepiness or unusual drowsiness

  • vomiting

Less common
  • Bad unusual or unpleasant (after) taste

  • bloody nose

  • body aches or pain

  • burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings

  • change in taste

  • clammy skin

  • congestion

  • continuing ringing or buzzing or other unexplained noise in ears

  • cough

  • dry mouth

  • dryness or soreness of throat

  • ear pain

  • false or unusual sense of well-being

  • fear or nervousness

  • feeling of warmth or heat

  • fever

  • floating feeling

  • flushing or redness of skin, especially on face and neck

  • headache

  • hearing loss

  • heat sensation on body

  • hoarseness

  • loss of appetite

  • nasal irritation

  • runny nose

  • shakiness

  • skin itching

  • sleeplessness

  • sneezing

  • stomach pain

  • stuffy nose

  • tender, swollen glands in neck

  • trouble in swallowing

  • trouble sleeping

  • unable to sleep

  • voice changes

  • weight loss

Rare
  • Sweating

  • unusual tiredness or weakness

Incidence not known
  • Dizziness or lightheadedness

  • feeling of constant movement of self or surroundings

  • lack or loss of strength

  • problems in speaking

  • sensation of spinning

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.


Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

See also: butorphanol Injection side effects (in more detail)



The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.


The use of the Thomson Reuters Healthcare products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Thomson Reuters Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON REUTERS HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Reuters Healthcare does not assume any responsibility or risk for your use of the Thomson Reuters Healthcare products.


More butorphanol Injection resources


  • Butorphanol Injection Side Effects (in more detail)
  • Butorphanol Injection Use in Pregnancy & Breastfeeding
  • Butorphanol Injection Drug Interactions
  • Butorphanol Injection Support Group
  • 23 Reviews for Butorphanol Injection - Add your own review/rating


Compare butorphanol Injection with other medications


  • Anesthesia
  • Anesthetic Adjunct
  • Labor Pain
  • Pain

Avibon




Avibon may be available in the countries listed below.


Ingredient matches for Avibon



Retinol

Retinol is reported as an ingredient of Avibon in the following countries:


  • France

International Drug Name Search

Benzetacil L.A.




Benzetacil L.A. may be available in the countries listed below.


Ingredient matches for Benzetacil L.A.



Benzylpenicillin

Benzylpenicillin benzathine (a derivative of Benzylpenicillin) is reported as an ingredient of Benzetacil L.A. in the following countries:


  • Colombia

International Drug Name Search

Tuesday, 27 September 2016

Carpipramine




Scheme

Rec.INN

CAS registry number (Chemical Abstracts Service)

0005942-95-0

Chemical Formula

C28-H38-N4-O

Molecular Weight

446

Therapeutic Category

Antidepressant, tricyclic

Chemical Name

[1,4'-Bipiperidine]-4'-carboxamide, 1'-[3-(10,11-dihydro-5H-dibenz[b,f]azepin-5-yl)propyl]-

Foreign Names

  • Carpipraminum (Latin)
  • Carpipramin (German)
  • Carpipramine (French)
  • Carpipramina (Spanish)

Generic Names

  • Carpipramine (OS: DCF)
  • Carbadipimidine (IS)
  • Carpipramine Hydrochloride (OS: JAN)
  • Carpipramine Dihydrochloride (IS)
  • PZ 1511 (IS)
  • RP 21679 (IS)

Brand Names

  • Defekton
    Tanabe Mitsubishi, Japan


  • Prazinil
    Pierre Fabre Médicament, France

International Drug Name Search

Glossary

DCFDénomination Commune Française
ISInofficial Synonym
JANJapanese Accepted Name
OSOfficial Synonym
Rec.INNRecommended International Nonproprietary Name (World Health Organization)

Click for further information on drug naming conventions and International Nonproprietary Names.

Epinefrina Life




Epinefrina Life may be available in the countries listed below.


Ingredient matches for Epinefrina Life



Epinephrine

Epinephrine hydrochloride (a derivative of Epinephrine) is reported as an ingredient of Epinefrina Life in the following countries:


  • Ecuador

International Drug Name Search

Avadène




Avadène may be available in the countries listed below.


Ingredient matches for Avadène



Estradiol

Estradiol hemihydrate (a derivative of Estradiol) is reported as an ingredient of Avadène in the following countries:


  • France

Gestodene

Gestodene is reported as an ingredient of Avadène in the following countries:


  • France

International Drug Name Search

Apo-Cephalex




Apo-Cephalex may be available in the countries listed below.


Ingredient matches for Apo-Cephalex



Cefalexin

Cefalexin is reported as an ingredient of Apo-Cephalex in the following countries:


  • Canada

  • Peru

International Drug Name Search

Auropan




Auropan may be available in the countries listed below.


Ingredient matches for Auropan



Auranofin

Auranofin is reported as an ingredient of Auropan in the following countries:


  • Georgia

International Drug Name Search

Avlosulfon




Avlosulfon may be available in the countries listed below.


Ingredient matches for Avlosulfon



Dapsone

Dapsone is reported as an ingredient of Avlosulfon in the following countries:


  • Ethiopia

International Drug Name Search

Aldara 5% Cream






Aldara 5% cream



Imiquimod



Read all of this leaflet carefully before you start using this medicine.


  • Keep this leaflet. You may need to read it again.

  • If you have any further questions, please ask your doctor or your pharmacist.

  • This medicine has been prescribed for you. Do not pass it on to others. It may harm them, even if their symptoms are the same as yours.

  • If any of the side effects gets serious, or if you notice any side effects not listed in this leaflet, please tell your doctor or pharmacist.




In this leaflet:


1. What Aldara cream is and what it is used for

2. Before you use Aldara cream

3. How to use Aldara cream

4. Possible side effects

5. How to store Aldara cream

6. Further information





What Is Aldara Cream And What It Is Used For


Aldara cream may be used for three different conditions. Your doctor may prescribe Aldara cream for the treatment of:


  • Warts (condylomata acuminata) on the surface of the genitals (sexual organs) and around the anus (back passage)

  • Superficial basal cell carcinoma.

    This is a common slow-growing form of skin cancer with a very small likelihood of spread to other parts of the body. It usually occurs in middle-aged and elderly people, especially those who are fair-skinned and is caused by too much sun exposure. If left untreated, basal cell carcinoma can disfigure, especially on the face – therefore early recognition and treatment are important.

  • Actinic keratosis

    Actinic keratoses are rough areas of skin found in people who have been exposed to a lot of sunshine over the course of their lifetime. Some are skin coloured, others are greyish, pink, red or brown. They can be flat and scaly, or raised, rough, hard and warty. Aldara should only be used for flat actinic keratoses on the face and scalp in patients with a healthy immune system where your doctor has decided that Aldara is the most appropriate treatment for you.

Aldara cream helps your body´s own immune system to produce natural substances which help fight your basal cell carcinoma, actinic keratosis or the virus that has caused your warts.




Before You Use Aldara Cream



Do not use Aldara cream :


  • If you are allergic to imiquimod (the active ingredient) or any of the ingredients of the cream.



Children and adolescents:


  • Use in children and adolescents is not recommended.



Take special care with Aldara cream:


  • If you have previously used Aldara cream or other similar preparations tell your doctor before starting this treatment.

  • Tell your doctor if you have problems with your immune system.

  • Do not use Aldara cream until the area to be treated has healed after previous drug or surgical treatment.

  • Avoid contact with the eyes, lips and nostrils. In the event of accidental contact, remove cream by rinsing with water.

  • Do not apply the cream internally.

  • Do not use more cream than your doctor has advised.

  • Do not cover the treated area with bandages or other dressings after you have applied Aldara cream.

  • If the treated site becomes too uncomfortable, wash the cream off with mild soap and water.

    As soon as the problem has stopped you may restart to apply the cream.

  • Tell your doctor if you have an abnormal blood count.

Because of the way Aldara works, there is a possibility that the cream may worsen existing inflammation in the treatment area.


  • If you are being treated for genital warts follow these additional precautions:


    Men with warts under the foreskin should pull the foreskin back each day and wash underneath it. If not washed daily the foreskin may be more likely to show signs of tightness, swelling and wearing away of the skin and result in difficulty in pulling it back. If these symptoms occur, stop the treatment immediately and call your doctor.


    If you have open sores: do not start using Aldara cream until after the sores have healed.


    If you have internal warts: do not use Aldara cream in the urethra (the hole from which urine is passed), the vagina (birth canal), the cervix (internal female organ), or anywhere inside your anus (rectum).


    Do not use this medication for more than one course if you have problems with your immune system, either due to illness or because of the medicines you are already taking. If you think this applies to you talk to your doctor.


    If you are HIV positive you should inform your doctor as Aldara cream has not been shown to be as effective in HIV positive patients. If you decide to have sexual relations while you still have warts, apply Aldara cream after - not before - sexual activity. Aldara cream may weaken condoms and diaphragms, therefore the cream should not be left on during sexual activity. Remember, Aldara cream does not protect against giving HIV or other sexually transmitted diseases to someone else.

  • If you are being treated for basal cell carcinoma or actinic keratosis follow these additional precautions:


    Do not use sunlamps or tanning beds, and avoid sunlight as much as possible during treatment with Aldara cream. Wear protective clothing and wide brimmed hats when outdoors.

Whilst using Aldara cream and until healed, the treatment area is likely to appear noticeably different from normal skin.




Using other medicines:


Please inform your doctor or pharmacist if you are taking or have recently taken any other medicines, including those obtained without a prescription.


There are no medicines known to be incompatible with Aldara cream.




Pregnancy and breast-feeding:


Ask your doctor or pharmacist for advice before taking any medicine.


You must tell your doctor if you are pregnant or intend to become pregnant. Your doctor will discuss the risks and benefits of using Aldara cream during pregnancy. Studies in animals do not indicate direct or indirect harmful effects in pregnancy.


Do not breast-feed your infant during treatment with Aldara cream, as it is not known whether imiquimod is secreted in human milk.




Important information about some of the ingredients of Aldara cream:


Methyl hydroxybenzoate (E218) and propyl hydroxybenzoate (E216) may cause allergic reactions (possibly delayed). Cetyl and stearyl alcohol may cause local skin reactions (e.g. contact dermatitis).





How To Use Aldara Cream



Children and adolescents:


Use in children and adolescents is not recommended.



Adults:


Always use Aldara cream exactly as your doctor has told you. Check with your doctor or pharmacist if you are not sure.


Wash hands carefully before and after applying the cream. Do not cover the treated area with bandages or other dressings after you have applied Aldara cream.


Open a new sachet each time you use the cream. Dispose of any cream left in the sachet after use. Do not save the opened sachet for use at a later date.


The treatment frequency and duration differ for genital warts, basal cell carcinoma and actinic keratosis (see specific instructions for each indication).





  • If you are being treated for genital warts:


Application Instructions – (Mon, Wed and Fri)



1. Before going to bed, wash your hands and the treatment area with mild soap and water. Dry thoroughly.
2. Open a new sachet and squeeze some cream onto your fingertip.
3. Apply a thin layer of Aldara cream onto clean, dry wart area and rub gently into the skin until cream vanishes.
4. After application of the cream, throw away the opened sachet and wash hands with soap and water.
5. Leave Aldara cream on the warts for 6 to 10 hours. Do not shower or bathe during this time.
6. After 6 to 10 hours wash the area where Aldara cream was applied with mild soap and water.


Apply Aldara cream 3 times per week. For example, apply the cream on Monday, Wednesday and Friday. One sachet contains enough cream to cover a wart area of 20 cm2 (approx. 3 square inches).


Men with warts under the foreskin should pull the foreskin back each day and wash underneath it (see section 2 “Take special care with Aldara cream:”)


Continue to use Aldara cream as instructed until your warts have completely gone (half the females who clear will do so in 8 weeks, half the males who clear will do so in 12 weeks but in some patients warts may clear as early as 4 weeks).


Do not use Aldara cream for more than 16 weeks in the treatment of each episode of warts.


If you have the impression that the effect of Aldara cream is too strong or too weak, talk to your doctor or pharmacist.




  • If you are being treated for basal cell carcinoma:


Application Instructions – (Mon, Tues, Wed, Thurs and Fri)


1. Before going to bed, wash your hands and the treatment area with mild soap and water. Dry thoroughly.

2. Open a new sachet and squeeze some cream onto your fingertip.

3. Apply Aldara cream to the affected area and 1cm (approx. 0.5 inch) around the affected area. Rub gently into the skin until the cream vanishes.

4. After application of the cream, throw away the opened sachet. Wash hands with soap and water.

5. Leave Aldara cream on the skin for about 8 hours. Do not shower or bathe during this time.

6. After about 8 hours, wash the area where Aldara cream was applied with mild soap and water.


Apply sufficient Aldara cream to cover the treatment area and 1 cm (about ½ an inch) around the treatment area each day for 5 consecutive days each week for 6 weeks. For example, apply the cream from Monday to Friday. Do not apply the cream on Saturday and Sunday.




  • If you are being treated for actinic keratosis


Application Instructions – (Mon, Wed and Fri)


1. Before going to bed, wash your hands and the treatment area with mild soap and water. Dry thoroughly.

2. Open a new sachet and squeeze some cream onto your fingertip.

3. Apply the cream to the affected area. Rub gently into the area until the cream vanishes.

4. After application of the cream, throw away the opened sachet. Wash hands with soap and water.

5. Leave Aldara cream on the skin for about 8 hours. Do not shower or bathe during this time.

6. After about 8 hours, wash the area where Aldara cream was applied with mild soap and water.


Apply Aldara cream 3 times per week. For example, apply the cream on Monday, Wednesday and Friday. One sachet contains enough cream to cover an area of 25 cm2 (approx. 4 square inches). Continue treatment for four weeks. Four weeks after finishing this first treatment, your doctor will assess your skin. If the lesions have not all disappeared, a further four weeks of treatment may be necessary.



If you use more Aldara cream than you should:


Wash the extra away with mild soap and water. When any skin reaction has gone you may then continue with your treatment.


If you accidentally swallow Aldara cream please contact your doctor.




If you forget to use Aldara cream:


If you miss a dose, apply cream as soon as you remember and then continue in your regular schedule. Do not apply the cream more than once per day.



If you have any further questions on the use of this product, ask your doctor or pharmacist.




Possible Side Effects


The frequency of side effects is classified as follows:


Very common side effects (likely to occur in more than 1 in 10 patients)


Common side effects (likely to occur in fewer than 1 in 10 patients)


Uncommon side effects (likely to occur in fewer than 1 in 100 patients)


Rare side effects (likely to occur in fewer than 1 in 1,000 patients)


Very rare side effects (likely to occur in fewer than 1 in 10,000 patients).


Like all medicines, Aldara cream can cause side effects, although not everybody gets them.


Tell your doctor or pharmacist as soon as possible if you do not feel well while you are using Aldara cream.


Some patients have experienced changes in skin colour in the area where Aldara cream was applied. While these changes have tended to improve with time, in some patients they may be permanent.


If your skin reacts badly when using Aldara cream, stop applying the cream, wash the area with mild soap and water and contact your doctor or pharmacist.


In some individuals a lowering of blood counts was noted. A lowering of blood counts might make you more susceptible to infections, make you bruise more easily or cause fatigue. If you notice any of these symptoms, tell your doctor.


Serious skin reactions have been reported rarely. If you experience skin lesions or spots on your skin that start out as small red areas and progress to look like mini targets, possibly with symptoms such as itching, fever, overall ill feeling, achy joints, vision problems, burning, painful or itchy eyes and mouth sores, stop using Aldara cream and tell your doctor immediately.


A small number of patients have experienced hair loss at the treatment site or surrounding area.


If any of the side effects gets serious, or if you notice any side effects not mentioned in this leaflet, please tell your doctor or pharmacist.



  • If you are being treated for genital warts:

Many of the undesirable effects of Aldara cream are due to its local action on your skin.



Very common effects include redness (61% patients), wearing away of the skin (30% patients), flakiness and swelling. Hardening under the skin, small open sores, a crust that forms during healing, and small bubbles under the skin may also occur. You might also feel itching (32% patients), a burning sensation (26% patients) or pain in areas where you have applied Aldara cream (8% patients). Most of these skin reactions are mild and the skin will return to normal within about 2 weeks after stopping treatment.



Commonly some patients (4% or less) have experienced headache, uncommonly fevers and flu like symptoms joint and muscle pains; prolapse of the womb; pain on intercourse in females; erection difficulties; increase in sweating; feeling sick; stomach and bowel symptoms; ringing in the ears; flushing; tiredness; dizziness; migraine; pins and needles; insomnia; depression; loss of appetite; swollen glands; bacterial, viral and fungal infections (e.g. cold sores); vaginal infection including thrush; cough and colds with sore throat.



Very rarely severe and painful reactions have occurred, particularly when more cream has been used than recommended. Painful skin reactions at the opening of the vagina have very rarely made it difficult for some women to pass urine. If this occurs you should seek medical help immediately.



  • If you are being treated for basal cell carcinoma:

Many of the undesirable effects of Aldara cream are due to its local action on your skin. Local skin reactions can be a sign that the drug is working as intended.



Very Commonly the treated skin may be slightly itchy.



Common effects include: pins and needles, small swollen areas in the skin, pain, burning, irritation, bleeding, redness or rash.


If a skin reaction becomes too uncomfortable during treatment, speak to your doctor. He/she may advise you to stop applying Aldara cream for a few days (i.e. to have a short rest from treatment).


If there is pus (matter) or other suggestion of infection, discuss this with your doctor. Apart from reactions in the skin, other common effects include swollen glands and back pain.



Uncommonly some patients experience changes at the application site (discharge, inflammation, swelling, scabbing, skin breakdown, blisters, dermatitis) or irritability, feeling sick, dry mouth, flu-like symptoms and tiredness.



  • If you are being treated for actinic keratosis

Many of the undesirable effects of Aldara cream are due to its local action on your skin. Local skin reactions can be a sign that the drug is working as intended.



Very commonly the treated skin may be slightly itchy.



Common effects include pain, burning, irritation or redness.


If a skin reaction becomes too uncomfortable during treatment, speak to your doctor. He/she may advise you to stop applying Aldara cream for a few days (i.e. to have a short rest from treatment).


If there is pus (matter) or other suggestion of infection, discuss this with your doctor. Apart from reactions in the skin, other common effects include headache, anorexia, nausea, muscle pain, joint pain and tiredness.



Uncommonly some patients experience changes at the application site (bleeding, inflammation, discharge, sensitivity, swelling, small swollen areas in the skin, pins and needles, scabbing, scarring, ulceration or a feeling of warmth or discomfort), or inflammation of the lining of the nose, stuffy nose, flu or flu-like symptoms, depression, eye irritation, swelling of the eyelid, throat pain, diarrhoea, actinic keratosis, redness, swelling of the face, ulcers, pain in extremity, fever, weakness or shivering.




How To Store Aldara Cream


Keep out of the reach and sight of children.


Do not store above 25°C.


Do not use after the expiry date stated on the label.


Sachets should not be re-used once opened.


Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist to dispose of medicines no longer required. These measures will help to protect the environment.




Further Information



What Aldara cream contains:


  • The active substance is imiquimod. Each sachet contains 250 mg cream (100 mg cream contains 5 mg imiquimod).

  • The other ingredients are isostearic acid, benzyl alcohol, cetyl alcohol, stearyl alcohol, white soft paraffin, polysorbate 60, sorbitan stearate, glycerol, methyl hydroxybenzoate (E218), propyl hydroxybenzoate (E216), xanthan gum, purified water.



What Aldara cream looks like and contents of the pack:


  • Each Aldara 5% cream sachet contains 250 mg of a white to slightly yellow cream.

  • Each box contains 12 or 24 single-use polyester/aluminium foil sachets. Not all pack sizes may be marketed.



Marketing Authorisation Holder:



Meda AB

Box 906

170 09 Solna

Sweden




Manufacturer :



3M Health Care Limited

Derby Road

Loughborough

Leicestershire

LE11 5SF

United Kingdom


For any information about this medicinal product, please contact the local representative of the Marketing Authorisation Holder.
































United Kingdom

Meda Pharmaceuticals Ltd.

Skyway House

Parsonage Road

Takeley

Bishop´s Stortford

CM22 6PU

Tel.:+ 44 845 460 0000





This leaflet was last approved in (04/2010)





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Glycerin and Blackcurrant Linctus (Boots Company plc)



(Glycerol, Sucrose)



Helps relieve sore throats and dry, tickly coughs



200 ml e



Read all of this label for full instructions.




Uses:



A linctus to relieve irritating tickly, dry coughs and sore throats.






Before you take this medicine




Do not take:



  • If you are allergic or intolerant to any of the ingredients


  • If you have an intolerance to some sugars, unless your doctor tells you to (this medicine contains glucose)



People with diabetes should take into account the carbohydrate content of this medicine (6.9 g per 10 ml).



You can take this medicine if your are pregnant or breastfeeding.





How to take this medicine



Check the cap seal is not broken before first use. If it is, do not take the medicine.



Adults and children of 5 years and over: Two 5 ml spoonfuls. Swallow this amount 3 or 4 times a day.



Children of 1 to 4 years: One 5 ml spoonful. Give this amount to your child to swallow 3 or 4 times a day.



Do not give to children under 1 year.



If symptoms do not go away talk to your pharmacist or doctor.



If you take or give too much: Talk to a pharmacist or doctor.





Possible side effects



This medicine is not expected to cause any side effects.



If you notice any side effect, please tell your pharmacist or doctor.



Keep all medicines out of the sight and reach of children.



Use by the date on the label edge.





Active ingredients



Each 10 ml of liquid contains Glycerol 1.5 ml, Sucrose 3.4 g.



Also contains: glucose (1.6 g), purified water, citric acid, sodium benzoate, anthocyanin, flavour (blackcurrant flavour and blackcurrant juice).




PL 00014/0307



Text prepared 12/07




Manufactured by the Marketing Authorisation holder




The Boots Company PLC

Nottingham

NG2 3AA




If you need more advice ask your pharmacist.



BTC19702 vD 13/06/08






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